Investigating energy dependency differences in triple negative breast cancer between racial groups
RACIAL DISPARITY IN THE ENERGY DEPENDENCY OF TRIPLE NEGATIVE BREAST CANCER
This study is looking at how the energy needs of triple negative breast cancer might differ between African American and Caucasian women, to help understand why African American women may face tougher challenges with this type of cancer and how it responds to treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10852885 on NIH RePORTER |
What this research studies
This research focuses on understanding the differences in energy dependency of triple negative breast cancer (TNBC) between African American and Caucasian women. It aims to explore how these differences affect the aggressiveness and treatment responses of the cancer. By examining the metabolic pathways, particularly the role of fatty acid β-oxidation and the Krebs cycle, the research seeks to identify why African American women with TNBC may have poorer outcomes. The study will utilize various biochemical analyses to assess the energy metabolism of cancer cells from both racial groups.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American women diagnosed with triple negative breast cancer.
Not a fit: Patients with non-triple negative breast cancer or those from racial groups other than African American may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, tailored treatments for triple negative breast cancer that consider racial disparities in energy metabolism.
How similar studies have performed: While there has been research on breast cancer disparities, this specific focus on energy dependency in TNBC is relatively novel and untested.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Kaipparettu, Benny Abraham — Baylor College of Medicine
- Study coordinator: Kaipparettu, Benny Abraham
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.