Investigating endothelial cells for better understanding of blood vessel disorders
Official title: Endothelial Cell Analytic Core
Funded at Augusta University · NIH-11103136 · Data updated 2026-11-12
This study is looking at special cells that line our blood vessels to better understand how they work and how we might improve treatments for blood vessel-related health issues.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Augusta University NIH-funded |
| Lab location | 1 site (Augusta, United States) |
| Project start | June 5, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $392,700 |
| NIH project number | 5P01HL160557-02 |
| Project ID | NIH-11103136 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with blood vessel disorders or related conditions who may benefit from advanced cellular therapies.
✕Less likely to help
Patients with conditions unrelated to blood vessel health or those not requiring cellular interventions may not benefit from this research.
What this research studies
This research focuses on isolating and characterizing endothelial cells, which line blood vessels, from both human tissues and mouse models. The team will utilize advanced techniques to purify these cells and analyze their properties, including metabolism and stress responses. Additionally, they will explore gene delivery methods to manipulate these cells for further study. This work aims to provide insights that could lead to improved treatments for conditions related to blood vessel disorders.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for blood vessel disorders and related conditions.
How similar studies have gone: Previous research has shown promise in using similar approaches to manipulate endothelial cells for therapeutic purposes.
Where this research is happening
-
Augusta University
Augusta, United States Active
Researchers
- Principal investigator: Lucas, Rudolf — Augusta University
- Study coordinator: Lucas, Rudolf
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.