Investigating emotional responses in infants at risk for autism

Multimodal investigation of emotional reactivity as a predictor of later psychopathology in infants at risk for ASD

NIH-funded research Yale University · NIH-11078688

This study is looking at how babies' emotional reactions might help us understand their future mental health, especially for those at risk of Autism Spectrum Disorder, so we can find ways to support them early on.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11078688 on NIH RePORTER

What this research studies

This research examines how emotional reactivity in infants, particularly those at risk for Autism Spectrum Disorder (ASD), can predict later mental health issues. By observing emotional responses from 4 to 30 months of age, the study aims to identify early signs of internalizing and externalizing disorders. The approach includes both behavioral observations and physiological measurements to capture a comprehensive view of emotional reactions. The goal is to improve early diagnosis and intervention strategies for children who may develop ASD or related conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are infants aged 4 to 30 months who have older siblings diagnosed with Autism Spectrum Disorder.

Not a fit: Patients who do not have a family history of Autism Spectrum Disorder or are outside the specified age range may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier identification and intervention for infants at risk for autism and related mental health issues.

How similar studies have performed: While there is limited evidence on emotional reactivity in toddlers with ASD, this research builds on existing findings and aims to fill significant gaps in understanding.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.