Investigating emerging infectious diseases and developing medical countermeasures.
Official title: Pitt RBL
Funded at University of Pittsburgh at Pittsburgh · NIH-10910178 · Data updated 2026-11-12
This study at the University of Pittsburgh is looking into how germs spread and cause illness, with the goal of creating better treatments and vaccines to help keep everyone safe during outbreaks and health emergencies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | August 18, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $2,594,826 |
| NIH project number | 5UC7AI180311-02 |
| Project ID | NIH-10910178 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit include individuals at risk for emerging infectious diseases or those involved in healthcare and public health.
✕Less likely to help
Patients with established chronic conditions unrelated to infectious diseases may not receive direct benefits from this research.
What this research studies
The Regional Biocontainment Laboratory at the University of Pittsburgh focuses on understanding how infectious diseases emerge and spread between hosts. This research involves studying the biology of pathogens and their interactions with hosts to develop new medical interventions and countermeasures. Patients may benefit from advancements in treatments and vaccines that arise from this work, particularly in response to pandemics and biological threats. The laboratory collaborates with various disciplines to ensure a comprehensive approach to infection biology.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective treatments and vaccines for emerging infectious diseases.
How similar studies have gone: Previous research in similar biocontainment settings has shown success in developing vaccines and treatments for infectious diseases.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Duprex, William Paul — University of Pittsburgh at Pittsburgh
- Study coordinator: Duprex, William Paul
Related research
Other NIH-funded projects on the same topics.
-
Elastomeric membranes for safer pelvic organ prolapse repair
A new 3D-printed elastomeric membrane made from polycarbonate urethane is being tested to replace stiff polypropylene meshes for pelvic organ prolapse in women, aiming to reduce complications.
-
Role of hyaluronan in egg development and ovarian reserve
This grant studies how the hyaluronan matrix in the ovary affects the aging of the female reproductive system and the pool of eggs available.
-
Regulatory switches that control imprinting in early human development
This grant studies how certain genes stay “one-copy” active in early development and what goes wrong in assisted reproduction, with a focus on imprinting disorders.
-
Identifying molecular signs of imprinting errors linked to fertility treatments
This grant studies how assisted reproductive technologies may cause imprinting errors in embryos and how these errors relate to certain birth conditions, with implications for families using infertility treatments.
-
Bioadhesive vaginal film for 7-day protection against HIV, HSV, and pregnancy
A vaginal film that slowly releases antibodies to prevent HIV, HSV, and unintended pregnancy for about a week from a single use.
-
Spermatogonial stem cell transplantation and culture in patients
Researchers are testing a way to transplant or grow sperm-producing cells back in boys and men who stored tissue before cancer treatment, to help them have biological children in the future.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.