Investigating early onset Alzheimer's disease and related dementias
Early Onset Alzheimer's Disease and Related Dementias: A Population-Based Approach to Identify Characteristics and Risk Factors
This study is looking at early onset Alzheimer's disease and related dementias in people under 65 to find out what factors, like heart health and lifestyle choices, might influence when symptoms start, so we can better understand this condition and help those affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11045713 on NIH RePORTER |
What this research studies
This research focuses on understanding early onset Alzheimer's disease and related dementias (EOD), which affects individuals diagnosed before the age of 65. By utilizing data from five large, diverse population-based studies, the research aims to identify characteristics and risk factors associated with EOD. The study will explore the impact of cardiovascular, lifestyle, and behavioral factors on the onset of EOD, as well as how genetic predispositions may influence the age at which symptoms appear. This comprehensive approach seeks to provide a clearer picture of EOD and its underlying causes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or related dementias before the age of 65, as well as those with a family history of these conditions.
Not a fit: Patients diagnosed with Alzheimer's disease after the age of 65 may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of early onset Alzheimer's disease, potentially enhancing the quality of life for affected individuals.
How similar studies have performed: This research builds on previous studies that have successfully identified risk factors for dementia, but it specifically targets the understudied area of early onset Alzheimer's disease.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Sedaghat, Sanaz — University of Minnesota
- Study coordinator: Sedaghat, Sanaz
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.