Investigating early life factors and screening patterns for young colorectal cancer patients
Official title: Examining Early Life Risk Factors and Patterns of Screening for Early-Onset Colorectal Cancer
Funded at Yale University · NIH-10997307 · Data updated 2026-11-12
This study is looking at what early life factors might lead to colorectal cancer in people under 50, and it also wants to see how screening for this cancer has changed over the years, especially with new guidelines and the effects of the COVID-19 pandemic, to help find better ways to catch it early.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | August 18, 2023 |
| Project end | August 17, 2025 |
| Funding year | 2024 |
| Award (this year) | $48,974 |
| NIH project number | 5F31CA281335-02 |
| Project ID | NIH-10997307 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals under 50 years of age who have been diagnosed with early-onset colorectal cancer or those who are part of the California birth cohort.
✕Less likely to help
Patients diagnosed with late-onset colorectal cancer (50 years and older) may not benefit directly from this research.
What this research studies
This research focuses on understanding the early life risk factors associated with early-onset colorectal cancer (EOCRC) in individuals under 50 years of age. It aims to identify specific birth characteristics and social factors that may contribute to the development of this aggressive form of cancer. Additionally, the study will evaluate how screening practices for EOCRC have changed over time and across different regions in the United States, particularly in light of recent changes in screening guidelines and the impact of the COVID-19 pandemic. By analyzing data from a large cohort, the research seeks to provide insights that could improve early detection and prevention strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved screening guidelines and preventive measures for early-onset colorectal cancer, potentially saving lives.
How similar studies have gone: While there have been studies on colorectal cancer screening, this research is novel in its focus on early life risk factors for early-onset cases.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Siddique, Arfan — Yale University
- Study coordinator: Siddique, Arfan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.