Investigating early detection and prevention of pancreatic cancer
TBEL Project 3
This study is looking at early signs of pancreatic cancer to find out what makes these signs turn into cancer, using samples from people, and it hopes to help doctors catch the disease earlier and find better ways to prevent it.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10922846 on NIH RePORTER |
What this research studies
This research focuses on understanding pancreatic cancer, particularly its early precursor lesions known as PanIN. By analyzing human PanIN samples, the study aims to identify both genetic and non-genetic factors that contribute to the progression of these lesions into cancer. The researchers will use advanced techniques, including three-dimensional reconstruction and whole exome sequencing, to correlate genomic changes with the development of neoplastic cells. This approach may lead to improved methods for early diagnosis and prevention of pancreatic cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of pancreatic cancer or those diagnosed with precursor lesions like PanIN.
Not a fit: Patients with advanced pancreatic cancer or those without any precursor lesions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and more effective prevention strategies for pancreatic cancer.
How similar studies have performed: Previous studies have shown promise in identifying genomic alterations in pancreatic cancer, suggesting that this approach may yield valuable insights.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Wood, Laura Delong — University of Tx Md Anderson Can Ctr
- Study coordinator: Wood, Laura Delong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.