NIH-funded research R01 grant

Investigating e-cigarette use trends among U.S. adolescents and young adults.

Official title: E-Cigarette Use among U.S. Adolescents and Young Adults: Longitudinal Associations with Tobacco Use and Health and Dimensions of Risk and Protection

Funded at University of Michigan at Ann Arbor · NIH-10984467 · Data updated 2026-11-12

This study looks at how young people in the U.S. use e-cigarettes over time and how it relates to smoking and other substances, helping us learn more about the health effects and what influences their choices.

More Tobacco Use research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor
NIH-funded
Lab location1 site (Ann Arbor, United States)
Project startDecember 15, 2022
Project endNovember 30, 2025
Funding year2025
Award (this year)$320,820
NIH project number5R01CA270546-03
Project IDNIH-10984467 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include U.S. adolescents and young adults aged 12 to 21 who use e-cigarettes or other tobacco products.

Less likely to help

Patients who are older than 21 or do not use e-cigarettes or tobacco products may not benefit from this research.

What this research studies

This research examines how e-cigarette use among adolescents and young adults in the U.S. evolves over time and its connections to cigarette smoking and other substance use. By analyzing data over several years, the study aims to understand the long-term effects of e-cigarettes on health and the factors that influence their use, including age, sex, race, and educational background. The research employs advanced statistical methods to address biases in self-reported data and to track changes in usage patterns. Participants will contribute to a better understanding of nicotine dependence and cessation efforts.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and intervention strategies for nicotine and tobacco use among young people.

How similar studies have gone: Previous research has shown that longitudinal studies can effectively track substance use trends, suggesting that this approach may yield valuable insights.

Where this research is happening

  • University of Michigan at Ann Arbor
    Ann Arbor, United States
    Active

Researchers

  • Principal investigator: Evans-Polce, Rebecca J. — University of Michigan at Ann Arbor
  • Study coordinator: Evans-Polce, Rebecca J.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.