Investigating drugs that affect the Hippo signaling pathway
Exploring Drugs Targeting Hippo Pathway
This study is looking at how some medications can affect a specific pathway in our cells that helps control their growth, with the hope of finding new treatment options for conditions where cell growth goes wrong.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11064181 on NIH RePORTER |
What this research studies
This research focuses on understanding how certain drugs can target the Hippo pathway, which plays a crucial role in regulating cell growth and development. By exploring the interactions of these drugs with the pathway, the research aims to identify potential therapeutic applications for various conditions. Patients may benefit from insights gained about how manipulating this pathway could lead to new treatment options for diseases related to cell growth abnormalities.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with conditions that may be influenced by the Hippo signaling pathway, such as certain cancers or growth disorders.
Not a fit: Patients with conditions unrelated to the Hippo pathway may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new drug therapies that improve treatment outcomes for patients with conditions related to the Hippo pathway.
How similar studies have performed: While the Hippo pathway is a well-studied area, the specific drug targeting approaches in this research may offer novel insights that have not been extensively tested.
Where this research is happening
Seattle, United States
- Fred Hutchinson Cancer Center — Seattle, United States (Active)
Researchers
- Principal investigator: Holland, Eric C. — Fred Hutchinson Cancer Center
- Study coordinator: Holland, Eric C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.