Investigating DNA damage and epigenetic changes related to aging
Official title: Core C: DNA Damage and Epigentic Changes
Funded at University of Minnesota · NIH-11117549 · Data updated 2026-11-12
This study is looking at how damage to our DNA and changes in our genes might affect how we age, with the goal of finding signs of aging and new ways to help us stay healthier as we get older.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | June 17, 2025 |
| Project end | May 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $254,100 |
| NIH project number | 1P30AG092751-01 |
| Project ID | NIH-11117549 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults experiencing age-related decline or disorders.
✕Less likely to help
Patients who are not experiencing age-related issues or are significantly younger may not benefit from this research.
What this research studies
This research focuses on understanding how DNA damage and changes in the epigenome contribute to the aging process. By examining the types of DNA damage that occur naturally in cells, the researchers aim to identify biomarkers that indicate aging and develop new therapeutic strategies to promote healthier aging. The study will utilize various assays to measure DNA damage and epigenetic alterations, which could lead to significant advancements in how we approach age-related health issues.
Why it matters
Potential benefit: If successful, this research could lead to new ways to delay aging and improve health span for older adults.
How similar studies have gone: Previous research has shown promise in understanding DNA damage and its role in aging, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Tretyakova, Natalia Y — University of Minnesota
- Study coordinator: Tretyakova, Natalia Y
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.