Investigating DNA changes related to autism spectrum disorder
Developmental methylomics of autism spectrum disorder
This study is looking at how changes in DNA might be linked to autism spectrum disorder (ASD) by comparing DNA from young adults with ASD to those without, and it also wants to see how things in the environment during pregnancy could affect these DNA changes, which could help identify people at risk for ASD earlier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-11013403 on NIH RePORTER |
What this research studies
This research focuses on understanding how DNA methylation, a chemical modification of DNA, may contribute to autism spectrum disorder (ASD). By analyzing DNA samples from young adults with ASD and matched controls, the study aims to uncover patterns of DNA methylation that could explain some of the unexplained genetic factors associated with ASD. The research will also explore how environmental factors may influence these DNA changes during prenatal development, potentially leading to early detection of individuals at risk for ASD.
Who could benefit from this research
Good fit: Ideal candidates for this research are young adults aged 18-25 who have been diagnosed with autism spectrum disorder.
Not a fit: Patients outside the age range of 18-25 or those without a diagnosis of autism spectrum disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection methods for autism spectrum disorder, allowing for timely interventions.
How similar studies have performed: Previous research has shown promise in understanding the role of DNA methylation in various neurodevelopmental disorders, suggesting that this approach may yield valuable insights.
Where this research is happening
Richmond, United States
- Virginia Commonwealth University — Richmond, United States (Active)
Researchers
- Principal investigator: Aberg, Karolina Anna — Virginia Commonwealth University
- Study coordinator: Aberg, Karolina Anna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.