Investigating diabetic foot ulcers and their treatment
Official title: UCSF Diabetic Foot Clinical Research Unit
Funded at University of California, San Francisco · NIH-11012833 · Data updated 2026-11-12
This study is looking at how to better understand and treat diabetic foot ulcers, so if you have one, you can join us to help find out what helps them heal faster and how social factors might play a role in your recovery.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 15, 2018 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $779,956 |
| NIH project number | 5U01DK119100-07 |
| Project ID | NIH-11012833 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are individuals with diabetes who are at risk of or currently experiencing diabetic foot ulcers.
✕Less likely to help
Patients without diabetes or those who do not have diabetic foot ulcers may not benefit from this research.
What this research studies
This research focuses on diabetic foot ulcers (DFUs), which affect a significant portion of individuals with diabetes. The UCSF Diabetic Foot Clinical Research Unit is part of a larger consortium aimed at improving the understanding and treatment of DFUs through the development and validation of biomarkers. Patients with DFUs will be enrolled in studies that assess their healing processes and the effectiveness of various treatment protocols. The research also aims to incorporate social factors that may influence health outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved healing rates and reduced amputation risks for patients with diabetic foot ulcers.
How similar studies have gone: Previous research has shown promise in biomarker development for diabetic foot ulcers, indicating that this approach could yield significant advancements.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Conte, Michael S — University of California, San Francisco
- Study coordinator: Conte, Michael S
Related research
Other NIH-funded projects on the same topics.
-
Improving Diabetic Foot Ulcer Offloading with User-Friendly Cast Walker Design
A small pilot study to see how different removable cast walker designs affect daily use and healing of diabetic foot ulcers.
-
Home-based exercise to help Veterans recover after healed diabetic foot ulcers
A home-based exercise program for Veterans who recently healed from a diabetic foot ulcer to improve walking and daily function.
-
How Medicaid Coverage Changes Diabetic Foot Care in Safety-Net Patients
This project looks at how new Medicaid coverage in California affects foot care, ED visits, and outcomes for adults with diabetes in safety-net populations.
-
Multi-targeted approach to help heal diabetic foot ulcers using electric fields and nitric oxide
A study to test a combo treatment using electric field stimulation and nitric oxide to boost healing in diabetic foot ulcers.
-
Wound fluid test to predict healing in diabetic foot ulcers
This project looks for chemical signals in the fluid from diabetic foot ulcers that could tell adults with diabetes whether a wound will heal with standard care or need a different treatment.
-
MTX-001 for healing diabetic foot ulcers in people with diabetes
A first–in–class biologic therapy called MTX-001 is being tested to help heal diabetic foot ulcers and reduce infection risk in adults with diabetes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.