Investigating diabetes that develops after acute pancreatitis
Official title: Indiana University clinical Center for acute pancreatitis and diabetes clinical research network
Funded at Indiana University Indianapolis · NIH-10898861 · Data updated 2026-11-12
This study is looking at how diabetes can develop after a serious pancreas problem called acute pancreatitis, and it's for adults who have had this condition; the goal is to learn more about what causes this type of diabetes so we can find better ways to help people manage it.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project start | September 17, 2020 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $272,392 |
| NIH project number | 5U01DK127382-05 |
| Project ID | NIH-10898861 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults who have experienced acute pancreatitis and may be at risk for developing type 3c diabetes.
✕Less likely to help
Patients who have not had acute pancreatitis or do not have diabetes may not benefit from this research.
What this research studies
This research focuses on pancreatogenic diabetes, also known as type 3c diabetes, which can develop as a complication of acute pancreatitis. The study aims to understand the various metabolic and immune-related factors that contribute to this condition by observing adults who have experienced acute pancreatitis. Participants will undergo extensive evaluations to identify the natural history of diabetes following pancreatitis, including the presence of autoantibodies and glucose tolerance issues. The research team at Indiana University is collaborating with experts in diabetes and pancreatic health to gather comprehensive data that could lead to better management strategies for affected individuals.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients who develop diabetes after acute pancreatitis.
How similar studies have gone: Previous research has indicated that understanding the relationship between pancreatitis and diabetes can lead to significant advancements in treatment, suggesting that this approach has potential for success.
Where this research is happening
-
Indiana University Indianapolis
Indianapolis, United States Active
Researchers
- Principal investigator: Fogel, Evan L — Indiana University Indianapolis
- Study coordinator: Fogel, Evan L
Related research
Other NIH-funded projects on the same topics.
-
Diabetes after acute pancreatitis: understanding and tracking progression
A patient-focused look at how diabetes can develop after an episode of acute pancreatitis, using data from a large, ongoing study and AI insights.
-
Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth
A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.
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Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium
A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.
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Diabetes after acute pancreatitis: a patient-focused network study
A program at Indiana University is studying how diabetes can develop after an acute pancreatitis episode, with new findings that could help doctors tailor care for adults who had pancreatitis.
-
Type 1 Diabetes in Acute Pancreatitis in Diabetes Patients at Stanford
A Stanford-led project helps people with brittle type 1 diabetes who also experience pancreatitis by following them in a long-term study to understand how acute pancreatitis affects diabetes.
-
Epidemiology and causes of diabetes after acute pancreatitis
A long-term study following people who have had acute pancreatitis to understand how often diabetes develops, why it happens, and how it progresses.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.