Investigating diabetes risk in patients with acute pancreatitis
Official title: Southern California Clinical Center of the Type 1 Diabetes in Acute Pancreatitis Consortium
Funded at Cedars-Sinai Medical Center · NIH-10911218 · Data updated 2026-11-12
This study is looking at how having acute pancreatitis might lead to different kinds of diabetes, and it's for people who have had this condition; by checking their insulin and sugar levels, researchers hope to find clues that could help prevent diabetes from developing after pancreatitis.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 16, 2020 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $283,999 |
| NIH project number | 5U01DK127403-05 |
| Project ID | NIH-10911218 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults who have recently experienced an episode of acute pancreatitis or recurrent acute pancreatitis and are currently non-diabetic.
✕Less likely to help
Patients who have already been diagnosed with diabetes or those who have not experienced acute pancreatitis will not benefit from this research.
What this research studies
This research focuses on understanding how acute pancreatitis (AP) can lead to different types of diabetes, including autoimmune forms. Patients who have experienced AP or recurrent AP will be recruited to undergo a series of tests that measure their insulin and glucose levels over time. The study aims to identify the metabolic and genetic factors that contribute to diabetes development in these patients. By closely monitoring these individuals, researchers hope to uncover patterns that could help predict and prevent diabetes after AP.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for diabetes that develops after acute pancreatitis.
How similar studies have gone: Previous research has shown promising results in understanding diabetes mechanisms in similar patient populations, indicating that this approach has potential for success.
Where this research is happening
-
Cedars-Sinai Medical Center
Los Angeles, United States Active
Researchers
- Principal investigator: Goodarzi, Mark — Cedars-Sinai Medical Center
- Study coordinator: Goodarzi, Mark
Related research
Other NIH-funded projects on the same topics.
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Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth
A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.
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Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium
A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.
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Type 1 Diabetes in Acute Pancreatitis in Diabetes Patients at Stanford
A Stanford-led project helps people with brittle type 1 diabetes who also experience pancreatitis by following them in a long-term study to understand how acute pancreatitis affects diabetes.
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Type 1 Diabetes after Acute Pancreatitis: Immune Clues from the Pacific Northwest
A multi-center study follows adults after an acute pancreatitis episode to understand how some develop Type 1 diabetes and what immune factors are involved.
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Diabetes After Acute Pancreatitis: Understanding Progression and Genetics at Cedars-Sinai
This grant supports Cedars-Sinai’s clinical center as part of a national effort to study why some adults develop brittle type 1 diabetes after an acute pancreatitis episode and how genes influence this risk.
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Understanding how acute pancreatitis may lead to type 1 diabetes
This study is looking at how having acute pancreatitis might lead to type 1 diabetes, and it aims to find early warning signs and risk factors to help identify people who could be at risk for developing diabetes after pancreatitis.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.