Investigating dementia and its risk factors in Native American communities
Dementia prevalence, APOE, and blood-based biomarkers of AD in Native American communities
['FUNDING_R01'] · UNIVERSITY OF MINNESOTA · NIH-11076226
This study is looking at how common Alzheimer's disease is in Native American communities and aims to find out what makes it different for them, including genetic factors, to help improve how we diagnose and treat dementia in these groups.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MINNESOTA (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-11076226 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the prevalence of dementia, specifically Alzheimer's disease, in Native American communities. It aims to identify unique risk factors and the role of genetic markers, such as APOE ε4, in these populations. By utilizing blood-based biomarkers, the study seeks to improve diagnostic methods and treatment approaches tailored to Native Americans. The research will also explore the types of dementia present in these communities, which are currently not well-documented.
Who could benefit from this research
Good fit: Ideal candidates for this research include Native American individuals who may be at risk for Alzheimer's disease or other forms of dementia.
Not a fit: Patients who do not identify as Native American or those without any risk factors for dementia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and effective treatments for Alzheimer's disease specifically designed for Native American populations.
How similar studies have performed: While there have been advancements in dementia research, this specific focus on Native American communities and their unique risk factors is relatively novel and underexplored.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- UNIVERSITY OF MINNESOTA — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MANTYH, WILLIAM G — UNIVERSITY OF MINNESOTA
- Study coordinator: MANTYH, WILLIAM G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome