Investigating corneal injury from chemical exposure
Late/chronic corneal injury following threat chemical exposure
['FUNDING_R01'] · UNIVERSITY OF MISSOURI-COLUMBIA · NIH-10903728
This study is looking at how certain chemicals, like Carbofuran and Chlorine, can harm your eyes and cause vision problems, with the goal of finding better treatments for people affected by these chemicals.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MISSOURI-COLUMBIA (nih funded) |
| Locations | 1 site (COLUMBIA, UNITED STATES) |
| Trial ID | NIH-10903728 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how exposure to certain chemicals, specifically Carbofuran and Chlorine, leads to chronic corneal injury and vision loss. By examining the mechanisms behind this damage, the study aims to identify how dysfunctional cellular processes contribute to corneal health issues. The research employs both animal models and human-derived corneal cultures to explore these mechanisms rigorously. Patients may benefit from insights gained that could lead to improved treatments for those affected by chemical exposure.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced exposure to Carbofuran or Chlorine and are suffering from corneal injuries or vision loss.
Not a fit: Patients who have not been exposed to these specific chemicals or do not have corneal injuries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for patients suffering from corneal injuries due to chemical exposure.
How similar studies have performed: Previous studies have shown promising results in understanding corneal damage mechanisms, but this specific approach is novel and aims to fill significant knowledge gaps.
Where this research is happening
COLUMBIA, UNITED STATES
- UNIVERSITY OF MISSOURI-COLUMBIA — COLUMBIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MOHAN, RAJIV RAVINDRA — UNIVERSITY OF MISSOURI-COLUMBIA
- Study coordinator: MOHAN, RAJIV RAVINDRA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.