Investigating colorectal cancer risks in survivors of childhood and young adult cancers
International Study of Subsequent Colorectal Cancer Among Survivors of Childhood, Adolescent, and Young Adult Cancers (I-SCRY)
This study is looking at how past cancer treatments might affect the chances of developing colorectal cancer later in life for people who survived childhood, adolescent, or young adult cancers, and it aims to help these survivors understand their long-term health risks.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10791757 on NIH RePORTER |
What this research studies
This research focuses on understanding the risk of developing colorectal cancer (CRC) in survivors of childhood, adolescent, and young adult cancers. It aims to analyze data from over 51,000 cancer survivors to identify how previous treatments, such as radiotherapy and chemotherapy, may influence the likelihood of developing CRC later in life. By pooling data from multiple international cohorts, the study seeks to uncover critical risk factors and mortality rates associated with subsequent CRCs. This comprehensive approach will help clarify the long-term health implications for these survivors.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have survived childhood, adolescent, or young adult cancers and are at risk for developing subsequent colorectal cancer.
Not a fit: Patients who have not survived childhood or young adult cancers may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved screening and prevention strategies for colorectal cancer in young cancer survivors.
How similar studies have performed: Previous research has indicated elevated risks of subsequent malignancies in cancer survivors, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Moskowitz, Chaya — Sloan-Kettering Inst Can Research
- Study coordinator: Moskowitz, Chaya
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.