NIH-funded research U01 cooperative agreement

Investigating colorectal cancer risk factors and blood biomarkers based on tumor types

Official title: Colorectal cancer risk factors, risk prediction and blood-based biomarker by tumor consensus molecular subtype

Funded at University of Kansas Medical Center · NIH-10591999 · Data updated 2026-11-12

This study is looking at different types of colorectal cancer to find out how they behave and what makes some people more at risk, so that we can create better ways to catch it early and help those at higher risk with more personalized screening options.

More Colorectal Cancer research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Kansas Medical Center
NIH-funded
Lab location1 site (Kansas City, United States)
Project startSeptember 20, 2019
Project endAugust 31, 2025
Funding year2021
Award (this year)$222,027
NIH project number7U01CA222163-04
Project IDNIH-10591999 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals at high risk for colorectal cancer, particularly those with a family history or genetic predispositions.

Less likely to help

Patients with non-colorectal cancers or those who do not have risk factors for colorectal cancer may not benefit from this research.

What this research studies

This research focuses on understanding the different types of colorectal cancer (CRC) and their associated risk factors. It aims to improve early detection by examining blood-based biomarkers linked to specific tumor subtypes, which may have varying aggressiveness and biological characteristics. By identifying these subtypes, the study seeks to enhance risk prediction and develop tailored screening strategies for individuals at higher risk. Patients may benefit from more personalized prevention and early detection methods based on their tumor profile.

Why it matters

Potential benefit: If successful, this research could lead to improved early detection and prevention strategies for colorectal cancer, potentially reducing morbidity and mortality.

How similar studies have gone: Other research has shown promise in using tumor subtypes to tailor cancer screening and treatment, indicating that this approach may lead to significant advancements.

Where this research is happening

  • University of Kansas Medical Center
    Kansas City, United States
    Active

Researchers

  • Principal investigator: Davis, Jennifer Sarah — University of Kansas Medical Center
  • Study coordinator: Davis, Jennifer Sarah

Related research

Other NIH-funded projects on the same topics.

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  • Improving colorectal cancer screening and follow-up care.

    This study is working to help more people get screened for colorectal cancer and receive the follow-up care they need, especially those who haven't been screened much before, so that everyone can have better access to important health checks and improve their overall health.

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    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11631673

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.