Investigating colorectal cancer risk factors and blood biomarkers based on tumor types
Colorectal cancer risk factors, risk prediction and blood-based biomarker by tumor consensus molecular subtype
This study is looking at different types of colorectal cancer to find out how they behave and what makes some people more at risk, so that we can create better ways to catch it early and help those at higher risk with more personalized screening options.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kansas Medical Center NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project ID | NIH-10591999 on NIH RePORTER |
What this research studies
This research focuses on understanding the different types of colorectal cancer (CRC) and their associated risk factors. It aims to improve early detection by examining blood-based biomarkers linked to specific tumor subtypes, which may have varying aggressiveness and biological characteristics. By identifying these subtypes, the study seeks to enhance risk prediction and develop tailored screening strategies for individuals at higher risk. Patients may benefit from more personalized prevention and early detection methods based on their tumor profile.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at high risk for colorectal cancer, particularly those with a family history or genetic predispositions.
Not a fit: Patients with non-colorectal cancers or those who do not have risk factors for colorectal cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection and prevention strategies for colorectal cancer, potentially reducing morbidity and mortality.
How similar studies have performed: Other research has shown promise in using tumor subtypes to tailor cancer screening and treatment, indicating that this approach may lead to significant advancements.
Where this research is happening
Kansas City, United States
- University of Kansas Medical Center — Kansas City, United States (Active)
Researchers
- Principal investigator: Davis, Jennifer Sarah — University of Kansas Medical Center
- Study coordinator: Davis, Jennifer Sarah
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.