Investigating cognitive issues related to blood vessel and gut problems after COVID-19.
Cognitive sequelae of cerebrovascular and gut dysfunction in post-acute COVID-19 syndrome.
This study is looking at how COVID-19, even in mild cases, might cause ongoing brain fog and thinking problems by affecting blood vessels and gut health, and it's for people who have recovered from the virus and want to understand their lingering symptoms better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lovelace Biomedical Research Institute NIH-funded |
| Lab location | 1 site (Albuquerque, United States) |
| Project ID | NIH-11097264 on NIH RePORTER |
What this research studies
This research explores the cognitive challenges faced by individuals recovering from COVID-19, particularly those who experienced mild or asymptomatic cases. It aims to understand how damage to blood vessels and the gut may contribute to persistent symptoms like 'brain fog' and cognitive deficits. By examining the role of the gut microbiome and the effects of the virus on the neurovascular unit, the study seeks to uncover indirect mechanisms that lead to chronic cognitive dysfunction. Participants may undergo assessments of their cognitive functions and gut health to help identify these connections.
Who could benefit from this research
Good fit: Ideal candidates are adults aged 21 and older who have experienced cognitive symptoms after recovering from COVID-19.
Not a fit: Patients who have not had COVID-19 or those without cognitive symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for cognitive impairments following COVID-19.
How similar studies have performed: While some studies have explored cognitive effects of COVID-19, this research focuses on novel indirect mechanisms, making it a relatively new approach.
Where this research is happening
Albuquerque, United States
- Lovelace Biomedical Research Institute — Albuquerque, United States (Active)
Researchers
- Principal investigator: Vakhtin, Andrei a — Lovelace Biomedical Research Institute
- Study coordinator: Vakhtin, Andrei a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.