Investigating cognitive impairment in older adults with prediabetes and type 2 diabetes
Alzheimer's Disease and Alzheimer's Disease Related Dementias in Prediabetes and Type 2 Diabetes: The Diabetes Prevention Program Outcomes Study AD/ADRD Project
This study is looking at how prediabetes and type 2 diabetes might impact thinking and memory in older adults, and it aims to find ways to help prevent these issues by understanding different health factors and habits.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11162996 on NIH RePORTER |
What this research studies
This research explores how prediabetes and type 2 diabetes affect cognitive function in older adults, particularly focusing on the risk factors and mechanisms that contribute to cognitive decline. It aims to understand the role of various factors such as neuropathology, glycemia, and physical activity in this high-risk population. By utilizing the Diabetes Prevention Program Outcomes Study cohort, the research will gather detailed information on participants' health and cognitive status to identify potential interventions. The findings could lead to better strategies for preventing cognitive impairment in individuals with diabetes.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above who have been diagnosed with prediabetes or type 2 diabetes.
Not a fit: Patients without prediabetes or type 2 diabetes, or those under 65 years of age, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for cognitive decline in older adults with diabetes.
How similar studies have performed: Previous research has shown that understanding the relationship between diabetes and cognitive impairment can lead to significant advancements in treatment approaches.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Luchsinger, Jose Alejandro — Columbia University Health Sciences
- Study coordinator: Luchsinger, Jose Alejandro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.