Investigating cognitive impairment in older adults with prediabetes and type 2 diabetes
Alzheimer's Disease and Alzheimer's Disease Related Dementias in Prediabetes and Type 2 Diabetes: The Diabetes Prevention Program Outcomes Study AD/ADRD Project
This study is looking at how prediabetes and type 2 diabetes might impact thinking and memory in older adults, especially those at risk for Alzheimer's and similar conditions, to find ways to help prevent or treat cognitive decline.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10924046 on NIH RePORTER |
What this research studies
This research examines how prediabetes and type 2 diabetes affect cognitive function in older adults, particularly focusing on Alzheimer's disease and related dementias. It aims to identify the risk factors and mechanisms that contribute to cognitive decline in this high-risk population. The study will utilize data from the Diabetes Prevention Program Outcomes Study, which includes detailed health information about participants. By exploring various factors such as metabolic health, medication effects, and physical activity, the research seeks to uncover insights that could lead to better prevention and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above who have been diagnosed with prediabetes or type 2 diabetes.
Not a fit: Patients who are younger than 65 or do not have prediabetes or type 2 diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of cognitive impairment in older adults with diabetes, potentially reducing the risk of Alzheimer's disease.
How similar studies have performed: Previous research has shown promising results in understanding the links between diabetes and cognitive decline, making this approach both relevant and potentially impactful.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Luchsinger, Jose Alejandro — Columbia University Health Sciences
- Study coordinator: Luchsinger, Jose Alejandro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.