Investigating chronic respiratory failure in children after sepsis
Official title: Timing and risk factors for developing chronic respiratory failure after pediatric sepsis
Funded at University of Michigan at Ann Arbor · NIH-10785849 · Data updated 2026-11-12
This study is looking at how and when kids who have survived sepsis might develop chronic respiratory failure, so we can find ways to prevent it and improve their care.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $158,933 |
| NIH project number | 1R03TR004798-01 |
| Project ID | NIH-10785849 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who have been hospitalized for sepsis.
✕Less likely to help
Patients who have not experienced sepsis or are older than 11 years may not benefit from this research.
What this research studies
This research focuses on understanding how and when chronic respiratory failure develops in children who have survived sepsis. The team will analyze national health data to identify patterns of onset and risk factors associated with this condition. By examining both in-hospital and post-discharge occurrences, the research aims to uncover modifiable factors that could help prevent this serious complication. The findings could lead to improved care strategies for pediatric patients recovering from sepsis.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and management strategies for chronic respiratory failure in children recovering from sepsis.
How similar studies have gone: Previous research has indicated a significant incidence of chronic respiratory failure in pediatric sepsis survivors, suggesting that this area of investigation is both relevant and necessary.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Carlton, Erin Fitzgerald — University of Michigan at Ann Arbor
- Study coordinator: Carlton, Erin Fitzgerald
Related research
Other NIH-funded projects on the same topics.
-
Graph-based AI to detect hospital-onset sepsis and find modifiable hospital factors
A patient-friendly program uses advanced computer models to spot hospital-onset sepsis early and uncover hospital practices that can be changed to reduce risk.
-
Understanding how to apply sepsis care guidelines in ICU patients with respiratory failure
A patient-friendly look at how hospitals can best use sepsis care bundles to save lives for people with breathing problems in the ICU.
-
Understanding which patients and hospital care pathways affect outcomes after ICU vs ward care for ARF and sepsis
A big study using hospital records to figure out which patients with acute respiratory failure and sepsis do best when admitted to ICUs versus general wards.
-
Understanding how care decisions affect outcomes for patients with breathing problems and sepsis
This project looks at hospital records to understand how decisions about where patients with severe breathing issues and sepsis receive care affect their recovery.
-
Improving sepsis care for patients with breathing failure
This project tries new ways to help hospitals deliver sepsis treatments faster for people with sepsis or acute respiratory failure.
-
Understanding the risks of acute respiratory failure in patients with hospital-onset sepsis
This study looks at how patients with hospital-onset sepsis might face different chances of developing breathing problems, and it aims to find better ways to treat those at higher risk so they can get the care they need to feel better.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.