Investigating chronic pain in people living with HIV
EcoHIV and neuropathic pain
['FUNDING_R21'] · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · NIH-10928806
This study is looking at how certain proteins from the HIV virus might cause ongoing nerve pain in people with HIV, and it aims to create a mouse model to help researchers find better ways to manage this pain for patients.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS RIO GRANDE VALLEY (nih funded) |
| Locations | 1 site (EDINBURG, UNITED STATES) |
| Trial ID | NIH-10928806 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding chronic neuropathic pain in individuals living with HIV, particularly how different viral proteins contribute to this condition. The study aims to develop a suitable animal model that mimics the chronic pain experienced by these patients, allowing researchers to explore the underlying mechanisms and potential therapeutic strategies. By using EcoHIV-infected mice, the research will assess behavioral and pathological changes associated with neuropathic pain, providing insights that could lead to better pain management for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who are living with HIV and experiencing chronic pain.
Not a fit: Patients who are not living with HIV or do not experience chronic pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for chronic pain in individuals living with HIV.
How similar studies have performed: While chronic pain in HIV patients is an understudied area, similar research approaches have shown promise in understanding pain mechanisms in other conditions.
Where this research is happening
EDINBURG, UNITED STATES
- UNIVERSITY OF TEXAS RIO GRANDE VALLEY — EDINBURG, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BENAMAR, KHALID — UNIVERSITY OF TEXAS RIO GRANDE VALLEY
- Study coordinator: BENAMAR, KHALID
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus