Investigating changes in the cerebellum and their effects on motor and cognitive functions in older adults.
A longitudinal investigation of the cerebellum in adulthood: anatomical and network changes, motor function, and cognition
This study is looking at how the brain changes as we get older and how those changes can affect our movement and thinking, especially in older adults, to help tell the difference between normal aging and signs of conditions like Alzheimer's, while also exploring how hormones might play a role for men and women.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas A&m University NIH-funded |
| Lab location | 1 site (College Station, United States) |
| Project ID | NIH-10669668 on NIH RePORTER |
What this research studies
This research explores how the cerebellum, a crucial part of the brain, changes as people age and how these changes affect movement and thinking abilities. By examining older adults, the study aims to identify patterns of normal aging versus those that may indicate conditions like Alzheimer's disease. The research will also consider differences between men and women, particularly how hormonal changes may influence brain health. Participants may undergo non-invasive brain stimulation to assess its effects on cerebellar function.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those over 21 years, who may be experiencing cognitive or motor function declines.
Not a fit: Patients who are younger than 21 or those without any cognitive or motor function issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for maintaining motor and cognitive functions in older adults, enhancing their quality of life.
How similar studies have performed: Previous research has shown promising results in understanding the role of the cerebellum in aging, but this specific focus on its changes in older adults is relatively novel.
Where this research is happening
College Station, United States
- Texas A&m University — College Station, United States (Active)
Researchers
- Principal investigator: Bernard, Jessica Ann — Texas A&m University
- Study coordinator: Bernard, Jessica Ann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.