Investigating changes in pain-related nerve tissues from organ donors and surgical patients
Human Tissue Procurement and Processing Core
This study is looking at nerve tissues from patients with chronic pain to learn more about how pain works, and if you're having certain surgeries, you might be able to help by donating a small tissue sample that could lead to better pain treatments in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Dallas NIH-funded |
| Lab location | 1 site (Richardson, United States) |
| Project ID | NIH-10930061 on NIH RePORTER |
What this research studies
This research focuses on the collection and analysis of human dorsal root ganglia (DRG) and spinal cord tissues to understand how these nerve tissues change in patients with chronic pain. By collaborating with organ transplant agencies, the project aims to recover tissues from organ donors and surgical patients, creating a valuable resource for studying pain mechanisms. The research will develop protocols for tissue recovery and generate datasets that could lead to new insights in pain therapy. Patients undergoing specific surgeries may contribute to this research by providing tissue samples that can help answer critical questions about chronic pain.
Who could benefit from this research
Good fit: Ideal candidates for participation include patients undergoing surgeries that involve the recovery of nerve tissues, particularly those with chronic pain conditions.
Not a fit: Patients who do not have chronic pain or are not undergoing relevant surgical procedures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating chronic pain conditions.
How similar studies have performed: Previous research has shown promise in using human tissue samples to study pain mechanisms, indicating that this approach could yield valuable insights.
Where this research is happening
Richardson, United States
- University of Texas Dallas — Richardson, United States (Active)
Researchers
- Principal investigator: Shiers, Stephanie — University of Texas Dallas
- Study coordinator: Shiers, Stephanie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.