Investigating Canagliflozin's effects on brain health and aging

Who could benefit from this research

What this research studies

This research explores how Canagliflozin, a medication typically used for diabetes, may protect the brain and improve cognitive function in older adults. The study focuses on understanding how this drug can reduce neuroinflammation and enhance brain health as people age. By examining its effects in animal models, researchers aim to uncover the potential benefits of Canagliflozin for preventing or alleviating conditions like Alzheimer's disease. If successful, this research could lead to new treatment options for age-related cognitive decline.

Why it matters

Where this research is happening

• Wayne State University
  Detroit, United States Active

Researchers

• Principal investigator: Sadagurski, Marianna — Wayne State University
• Study coordinator: Sadagurski, Marianna

Related research

Other NIH-funded projects on the same topics.

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• The effects of exercise on cognitive function and aging in older adults

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  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10980240

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.