Investigating brain swelling after a type of stroke
Official title: Radiographic markers and therapeutic targets of cerebral edema after SAH
Funded at University of Texas Hlth Sci Ctr Houston · NIH-11080382 · Data updated 2026-11-12
This study is looking at how to better understand and treat brain swelling that happens after a certain type of stroke, called subarachnoid hemorrhage, by using new imaging techniques and studying tiny molecules in the brain, with the hope of finding better ways to help patients recover.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $557,202 |
| NIH project number | 5R01NS131469-02 |
| Project ID | NIH-11080382 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have recently experienced a subarachnoid hemorrhage and are at risk for developing severe cerebral edema.
✕Less likely to help
Patients who have not experienced a subarachnoid hemorrhage or those with other types of strokes may not benefit from this research.
What this research studies
This research focuses on understanding severe brain swelling, known as cerebral edema, that occurs after subarachnoid hemorrhage (SAH), a type of stroke affecting many individuals each year. The study aims to develop new methods for measuring brain water content using advanced imaging techniques and to explore the role of specific microRNAs in the mechanisms of cerebral edema. By identifying these factors, the research seeks to pave the way for targeted therapies that could improve outcomes for patients suffering from SAH. Patients may be monitored through imaging and biological samples to assess the effectiveness of these potential treatments.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve recovery and reduce disability for patients who experience subarachnoid hemorrhage.
How similar studies have gone: Previous research has shown promise in using imaging techniques and biomarker analysis to understand and potentially treat cerebral edema, indicating that this approach may lead to meaningful advancements.
Where this research is happening
-
University of Texas Hlth Sci Ctr Houston
Houston, United States Active
Researchers
- Principal investigator: Choi, Huimahn Alex — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Choi, Huimahn Alex
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.