Investigating brain receptors related to cocaine use disorder
Assessing central muscarinic acetylcholine type-1 receptors in cocaine use disorder with 11C-LSN3172176.
This study is looking at how certain brain receptors are involved in cocaine addiction to find new ways to help people who are struggling with this issue.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11055793 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of muscarinic acetylcholine type-1 receptors in individuals with cocaine use disorder (CUD). By examining how these receptors function in the brain, particularly in areas associated with addiction, the study aims to uncover new therapeutic approaches for treating CUD. The research employs advanced imaging techniques to assess receptor activity and its relationship with cocaine use patterns. Through this innovative approach, the study seeks to provide insights that could lead to more effective treatments for those struggling with addiction.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cocaine use disorder who are seeking treatment options.
Not a fit: Patients who do not have a diagnosis of cocaine use disorder or those who are not currently using cocaine may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new pharmacotherapies that effectively reduce cravings and improve treatment outcomes for individuals with cocaine use disorder.
How similar studies have performed: Previous research has shown promising results in targeting brain receptors for addiction treatment, suggesting that this approach may lead to significant advancements in therapy for cocaine use disorder.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Angarita, Gustavo Adolfo — Yale University
- Study coordinator: Angarita, Gustavo Adolfo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.