Investigating brain processes related to cognitive and motivational deficits in early psychosis
Using a computational and network neuroscience framework to study pharmacological manipulations of state representation processes in early psychosis
This study is looking at how early psychosis affects the way the brain works, especially when it comes to thinking and motivation, and it aims to find out more about these challenges to help create better treatments for people experiencing these issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11109964 on NIH RePORTER |
What this research studies
This research focuses on understanding how certain brain processes are affected in individuals experiencing early psychosis, particularly in relation to cognitive and motivational challenges. By manipulating computational parameters and analyzing data from clinical assessments and EEG measures, the study aims to uncover the underlying mechanisms of these deficits. Participants will be drawn from a previous project and will undergo various evaluations to help identify specific brain dysfunctions that could inform personalized treatment strategies. The goal is to enhance our understanding of psychosis and improve interventions for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with early psychosis who exhibit cognitive and motivational deficits.
Not a fit: Patients with late-stage psychosis or those without cognitive and motivational impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized treatments for cognitive and motivational impairments in patients with early psychosis.
How similar studies have performed: Previous research has shown promise in using computational neuroscience approaches to understand brain dysfunctions in psychosis, suggesting that this methodology could yield valuable insights.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Vinogradov, Sophia — University of Minnesota
- Study coordinator: Vinogradov, Sophia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.