Investigating brain networks linked to disruptive behavior in children

Multimodal imaging biomarkers of cognitive control network deficits in youths with disruptive behavior

NIH-funded research Yale University · NIH-10908369

This study is looking at how certain parts of children's brains are connected and how that might relate to behaviors like aggression and not following rules, helping us understand what might cause these issues in kids aged 9 to 12.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-10908369 on NIH RePORTER

What this research studies

This research aims to explore how specific brain networks are associated with disruptive behavior disorders (DBD) in children, which include issues like aggression and noncompliance. By utilizing advanced imaging techniques, the study will analyze brain connectivity and structure, particularly focusing on the amygdala and prefrontal cortex. The research will leverage a large dataset of children aged 9-12 to identify potential biomarkers that could help predict disruptive behaviors. Ultimately, the goal is to enhance understanding of the underlying brain mechanisms that contribute to these behaviors.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 9-12 who display signs of disruptive behavior or have been diagnosed with disruptive behavior disorders.

Not a fit: Patients who do not exhibit disruptive behaviors or are outside the age range of 9-12 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic tools and interventions for children exhibiting disruptive behaviors.

How similar studies have performed: Previous research has shown promising results in identifying brain biomarkers related to behavioral disorders, suggesting that this approach may yield valuable insights.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.