Investigating brain networks involved in trauma-related memories
Multimodal imaging of hippocampal-cortical networks and mechanisms of trauma-related intrusions
This study is looking at how the brain handles unwanted memories, like flashbacks and nightmares, in people with PTSD, to find better ways to help them feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mclean Hospital NIH-funded |
| Lab location | 1 site (Belmont, United States) |
| Project ID | NIH-10597248 on NIH RePORTER |
What this research studies
This research focuses on understanding how the brain processes intrusive memories associated with posttraumatic stress disorder (PTSD), such as flashbacks and nightmares. By using advanced imaging techniques, the study aims to explore the connections between the hippocampus and other brain regions that contribute to these distressing symptoms. The goal is to identify specific brain mechanisms that may lead to better treatment options for individuals suffering from PTSD. Participants will undergo imaging assessments to help researchers understand the neural basis of their trauma-related experiences.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with PTSD and experience intrusive memories.
Not a fit: Patients who do not have PTSD or are under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for PTSD by targeting the underlying brain mechanisms of intrusive memories.
How similar studies have performed: Previous research has shown promising results in understanding brain mechanisms related to PTSD, but this specific approach using multimodal imaging is relatively novel.
Where this research is happening
Belmont, United States
- Mclean Hospital — Belmont, United States (Active)
Researchers
- Principal investigator: Rosso, Isabelle M — Mclean Hospital
- Study coordinator: Rosso, Isabelle M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.