Investigating brain injury in preterm newborns with congenital heart disease
Brain Injury and Dysmaturation in Newborns with Congenital Heart Disease Born Preterm
This study is looking at how different heart surgeries for newborns with congenital heart disease might affect their brain development and risk of injury, especially for those born early, and it also checks if genetics play a role in their outcomes, all to help these little ones have better futures.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11053571 on NIH RePORTER |
What this research studies
This research focuses on understanding the risks of brain injury and neurodevelopmental issues in newborns who are both preterm and have congenital heart disease (CHD). By examining different surgical strategies used to treat heart defects, the study aims to determine how these interventions impact brain development and injury risk. The research will also include genetic evaluations to see how genetic factors may influence outcomes. This comprehensive approach aims to improve the long-term neurodevelopmental outcomes for affected infants.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns under 4 weeks old who are born preterm and diagnosed with congenital heart disease.
Not a fit: Patients who are not newborns or those without congenital heart disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that enhance brain development and reduce injury in newborns with congenital heart disease.
How similar studies have performed: Previous research has shown promising results in understanding brain injury in newborns with congenital conditions, making this approach both relevant and potentially impactful.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Mcquillen, Patrick Sean — University of California, San Francisco
- Study coordinator: Mcquillen, Patrick Sean
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.