Investigating brain imaging to understand cognitive decline in multiple sclerosis
Multi-scale, multi-modal imaging assessment of trajectories of cognitive impairment in Multiple Sclerosis
This study is looking at how multiple sclerosis affects thinking and memory by using special brain scans, and it's aimed at finding ways to create personalized treatments that can help keep your mind sharp.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10981498 on NIH RePORTER |
What this research studies
This research focuses on understanding cognitive impairment in patients with multiple sclerosis (MS) by using advanced brain imaging techniques. It employs diffusion MRI and functional MRI to analyze changes in brain structure and connectivity over time. By examining both macroscopic and microscopic brain changes, the study aims to identify specific brain networks associated with cognitive decline. The ultimate goal is to develop personalized therapies that can help preserve cognitive function in MS patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with multiple sclerosis who are experiencing cognitive impairment.
Not a fit: Patients with cognitive impairment due to conditions other than multiple sclerosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, targeted therapies that improve cognitive function in patients with multiple sclerosis.
How similar studies have performed: Previous research using similar imaging techniques has shown promise in understanding cognitive impairment in neurological conditions, suggesting potential for success in this approach.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Gauthier, Susan a — Weill Medical Coll of Cornell Univ
- Study coordinator: Gauthier, Susan a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.