Investigating brain imaging techniques for understanding dementia
Official title: Multi-scale and multi-modality imaging of neuropathology in VCID
Funded at New York University School of Medicine · NIH-10933527 · Data updated 2026-11-12
This study is working on new ways to take pictures of the brain to better understand how aging and diseases like Alzheimer's affect our thinking, and it's for anyone interested in learning more about how brain health changes over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 22, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $1,633,010 |
| NIH project number | 5U24NS135568-02 |
| Project ID | NIH-10933527 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with age-related cognitive decline or dementia, particularly those with Alzheimer's disease.
✕Less likely to help
Patients with early-stage cognitive impairment or those not diagnosed with dementia may not receive direct benefits from this research.
What this research studies
This research focuses on improving brain imaging methods to better understand the changes associated with age-related cognitive decline and dementia. By combining MRI and histopathology, the study aims to develop new techniques for analyzing brain tissue after death, which can provide insights into the mechanisms of diseases like Alzheimer's. The research team will create advanced imaging protocols and computational tools to analyze brain samples, helping to bridge the gap between in vivo and post-mortem studies. This approach could lead to a deeper understanding of how vascular issues contribute to cognitive impairment.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for patients with dementia.
How similar studies have gone: Previous research has shown promise in using combined imaging techniques to study neurodegeneration, indicating that this approach could yield valuable insights.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Ge, Yulin — New York University School of Medicine
- Study coordinator: Ge, Yulin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.