Investigating brain imaging and blood markers for Alzheimer's disease and related conditions
Neuroimaging and Plasma Biomarkers Core
This study is looking at how certain changes in the brain and blood can help us understand Alzheimer's disease and related memory problems, especially in people who might be at risk due to pre-diabetes or type 2 diabetes, so we can find better ways to help them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10924051 on NIH RePORTER |
What this research studies
This research focuses on using advanced brain imaging techniques and analyzing blood samples to identify biomarkers associated with Alzheimer's disease and related dementias. By conducting quality assurance and control activities, the study aims to ensure accurate measurements of brain health and neurodegeneration. The research will also explore the relationship between these biomarkers and cognitive outcomes in individuals at risk for cognitive impairment, particularly those with pre-diabetes and type 2 diabetes. This comprehensive approach seeks to enhance our understanding of the disease mechanisms and potential therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults aged 60 and above, particularly those with pre-diabetes or type 2 diabetes.
Not a fit: Patients who are not at risk for cognitive impairment or do not have Alzheimer's disease or related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for Alzheimer's disease and related dementias.
How similar studies have performed: Previous research has shown promise in using neuroimaging and plasma biomarkers to understand Alzheimer's disease, indicating that this approach has potential for success.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Nasrallah, Ilya M — Columbia University Health Sciences
- Study coordinator: Nasrallah, Ilya M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.