Investigating brain health in youth at risk for type 2 diabetes

Brain Health Across the Metabolic Continuum in Youth at Risk for T2D

NIH-funded research Washington University · NIH-10889982

This study is looking at how type 2 diabetes affects the brains of kids and teens, especially those who are overweight, to find out what might help keep their brains healthy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-10889982 on NIH RePORTER

What this research studies

This research focuses on understanding how type 2 diabetes (T2D) affects brain health in children and adolescents. It examines the relationship between obesity, metabolic dysfunction, and brain structure and function in youth diagnosed with T2D. By studying participants across different body mass indices, the research aims to identify factors that contribute to brain-related complications associated with T2D. The findings could help in developing targeted interventions to improve brain health in at-risk youth.

Who could benefit from this research

Good fit: Ideal candidates for participation include children and adolescents with obesity or those diagnosed with type 2 diabetes.

Not a fit: Patients who are not diagnosed with obesity or type 2 diabetes may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing brain complications in youth with type 2 diabetes.

How similar studies have performed: Previous research has shown that understanding the relationship between metabolic conditions and brain health can lead to significant insights, indicating that this approach has potential for success.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes MellitusAlzheimer's disease risk
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.