Investigating brain growth issues caused by alcohol exposure during pregnancy using advanced imaging techniques.
Functional consequences of fetal-alcohol-induced brain growth abnormalities identified with in utero MRI
This study is looking at how drinking alcohol during pregnancy can affect a baby's brain development, using advanced imaging techniques on monkeys to help us find ways to spot these issues early and provide better support for families.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-11031303 on NIH RePORTER |
What this research studies
This research focuses on understanding the neurological deficits caused by fetal alcohol exposure, known as fetal alcohol spectrum disorder (FASD). By utilizing advanced in utero MRI techniques, the study aims to identify abnormal brain development in fetuses exposed to alcohol during the first trimester. The research employs a rhesus macaque model to simulate human alcohol consumption patterns and assess the resulting brain abnormalities. The goal is to enhance early detection of FASD, which is crucial for implementing effective interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant individuals who consume alcohol during the first trimester and their children who may be at risk for FASD.
Not a fit: Patients who have not been exposed to alcohol during pregnancy or those whose children are already diagnosed with FASD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection and intervention strategies for children affected by fetal alcohol spectrum disorder.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to identify brain abnormalities in similar contexts, indicating a potential for success in this approach.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Cuzon Carlson, Verginia Carmella — Oregon Health & Science University
- Study coordinator: Cuzon Carlson, Verginia Carmella
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.