Investigating brain damage and inflammation in multiple sclerosis using advanced MRI techniques

Characterization of Whole Brain Demyelination and Axon Damage Using High-resolution Magnetic Resonance Imaging

['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-11179495

This study is looking at how multiple sclerosis affects the brain using advanced MRI scans to find new ways to spot early signs of the disease and track how it changes over time, which could help improve diagnosis and treatment for patients like you.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUT SOUTHWESTERN MEDICAL CENTER (nih funded)
Locations1 site (DALLAS, UNITED STATES)
Trial IDNIH-11179495 on ClinicalTrials.gov

What this research studies

This research focuses on understanding the effects of multiple sclerosis (MS) on the brain by using advanced magnetic resonance imaging (MRI) techniques. It aims to develop new imaging biomarkers that can detect early signs of MS and monitor its progression more effectively than current methods. By utilizing high-resolution imaging technologies, the study seeks to provide a clearer picture of axon and dendrite damage associated with MS. Patients may benefit from improved diagnostic tools and treatment monitoring as a result of this research.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with multiple sclerosis or those exhibiting symptoms suggestive of the disease.

Not a fit: Patients with other neurological disorders unrelated to multiple sclerosis may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier diagnosis and better monitoring of multiple sclerosis, ultimately improving patient outcomes.

How similar studies have performed: Previous research has shown promise in using advanced MRI techniques for studying brain conditions, suggesting that this approach could yield valuable insights into multiple sclerosis.

Where this research is happening

DALLAS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.