Investigating brain damage and inflammation in multiple sclerosis using advanced MRI techniques
Official title: Characterization of Whole Brain Demyelination and Axon Damage Using High-resolution Magnetic Resonance Imaging
Funded at Ut Southwestern Medical Center · NIH-11179495 · Data updated 2026-11-12
This study is looking at how multiple sclerosis affects the brain using advanced MRI scans to find new ways to spot early signs of the disease and track how it changes over time, which could help improve diagnosis and treatment for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | May 30, 2024 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $407,903 |
| NIH project number | 5R01NS125020-04 |
| Project ID | NIH-11179495 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with multiple sclerosis or those exhibiting symptoms suggestive of the disease.
✕Less likely to help
Patients with other neurological disorders unrelated to multiple sclerosis may not receive benefit from this research.
What this research studies
This research focuses on understanding the effects of multiple sclerosis (MS) on the brain by using advanced magnetic resonance imaging (MRI) techniques. It aims to develop new imaging biomarkers that can detect early signs of MS and monitor its progression more effectively than current methods. By utilizing high-resolution imaging technologies, the study seeks to provide a clearer picture of axon and dendrite damage associated with MS. Patients may benefit from improved diagnostic tools and treatment monitoring as a result of this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and better monitoring of multiple sclerosis, ultimately improving patient outcomes.
How similar studies have gone: Previous research has shown promise in using advanced MRI techniques for studying brain conditions, suggesting that this approach could yield valuable insights into multiple sclerosis.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Wang, Nian — Ut Southwestern Medical Center
- Study coordinator: Wang, Nian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.