Investigating brain connectivity in schizophrenia using advanced imaging techniques
Functional MRI in Schizophrenia
This study is looking at how a part of the brain called the hippocampus connects with other areas in people with schizophrenia, using a special imaging technique to see how the brain works when it's at rest, and it hopes to help us understand more about brain function in this condition.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Feinstein Institute for Medical Research NIH-funded |
| Lab location | 1 site (Manhasset, United States) |
| Project ID | NIH-10681202 on NIH RePORTER |
What this research studies
This research focuses on understanding how the hippocampus, a critical brain region, connects with other areas in individuals with schizophrenia. By employing a novel imaging technique called single-shot single-label background-suppressed dynamic arterial spin labeling, the study aims to measure resting-state functional connectivity in the brain. This approach seeks to clarify the role of the hippocampus in schizophrenia and improve the reliability of findings related to brain function in this condition. Patients may undergo non-invasive brain imaging to help researchers gather data on brain connectivity patterns.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with schizophrenia or related disorders.
Not a fit: Patients without a diagnosis of schizophrenia or those with other unrelated mental health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment strategies for schizophrenia.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to study brain connectivity, suggesting potential for success in this novel approach.
Where this research is happening
Manhasset, United States
- Feinstein Institute for Medical Research — Manhasset, United States (Active)
Researchers
- Principal investigator: He, Xiang — Feinstein Institute for Medical Research
- Study coordinator: He, Xiang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.