Investigating brain connectivity in aging and Alzheimer's disease

Who could benefit from this research

What this research studies

This research focuses on understanding how brain connectivity changes in healthy aging and Alzheimer's disease (AD) by using advanced imaging techniques. It employs high-resolution diffusion-weighted imaging (DWI) to examine the white matter pathways in the brain, which are crucial for cognitive functions like attention and memory. By comparing standard and high-resolution imaging methods, the study aims to provide insights into how these changes in connectivity relate to cognitive decline. Patients may undergo MRI scans to help researchers gather data on brain structure and function.

Why it matters

Where this research is happening

• Duke University
  Durham, United States Active

Researchers

• Principal investigator: Merenstein, Jenna L — Duke University
• Study coordinator: Merenstein, Jenna L

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.