Investigating brain connectivity changes in stroke patients with language impairment
Official title: Dynamic functional network connectivity and neuroplasticity in post-stroke aphasia
Funded at Boston University Medical Campus · NIH-10928147 · Data updated 2026-11-12
This study is looking at how the connections in the brain change for people with aphasia after a stroke, to help understand how these changes can improve their recovery and response to language therapy.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 18, 2023 |
| Project end | August 17, 2027 |
| Funding year | 2024 |
| Award (this year) | $53,974 |
| NIH project number | 5F30DC021092-02 |
| Project ID | NIH-10928147 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have experienced a stroke and are facing challenges with language and communication.
✕Less likely to help
Patients who have not had a stroke or do not experience aphasia may not benefit from this research.
What this research studies
This research focuses on understanding how brain connectivity changes in patients with aphasia after a stroke. Using advanced imaging techniques like functional MRI, the study will examine both static and dynamic connectivity in the brain to see how these changes relate to recovery and response to language therapy. By comparing the brain activity of stroke patients to healthy individuals, researchers aim to uncover patterns that could predict treatment outcomes and enhance rehabilitation strategies. The study will explore the relationship between short-term brain connectivity dynamics and long-term brain plasticity in individuals recovering from stroke.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for stroke patients with aphasia, enhancing their recovery and communication abilities.
How similar studies have gone: Previous research has shown promising results in using functional connectivity measures to predict treatment responses in stroke patients, indicating that this approach has potential for success.
Where this research is happening
-
Boston University Medical Campus
Boston, United States Active
Researchers
- Principal investigator: Falconer, Isaac B — Boston University Medical Campus
- Study coordinator: Falconer, Isaac B
Related research
Other NIH-funded projects on the same topics.
-
Neural signals linked to recovery from aphasia after stroke
This grant follows people who recently had a stroke and aphasia to understand why some recover language abilities better than others.
-
Computational modeling of language in bilingual adults after stroke and with neurodegenerative conditions
A computer-based study will model how bilingual Spanish-English speakers experience language changes after stroke and with neurodegenerative disorders, to inform better care for affected patients.
-
Restoring speech with a brain implant for stroke-related aphasia
A study at UC Davis aims to help people who have language trouble after a stroke by using a tiny brain implant to turn brain signals into spoken words.
-
Predicting language recovery after stroke using AI
A new AI-based project uses brain scans and personal data to forecast how aphasia may progress after a stroke, with the goal of guiding personalized treatment.
-
Neural signals of getting speech back after stroke
This grant studies how the brain changes as people recover speech after a stroke, to help predict and improve language recovery.
-
How the brain recovers language after a stroke
This research follows people with aphasia after stroke to find brain and behavior signs that predict who will regain speech and language.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.