Investigating brain connectivity changes in stroke patients with language impairment
Dynamic functional network connectivity and neuroplasticity in post-stroke aphasia
This study is looking at how the connections in the brain change for people with aphasia after a stroke, to help understand how these changes can improve their recovery and response to language therapy.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10928147 on NIH RePORTER |
What this research studies
This research focuses on understanding how brain connectivity changes in patients with aphasia after a stroke. Using advanced imaging techniques like functional MRI, the study will examine both static and dynamic connectivity in the brain to see how these changes relate to recovery and response to language therapy. By comparing the brain activity of stroke patients to healthy individuals, researchers aim to uncover patterns that could predict treatment outcomes and enhance rehabilitation strategies. The study will explore the relationship between short-term brain connectivity dynamics and long-term brain plasticity in individuals recovering from stroke.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have experienced a stroke and are facing challenges with language and communication.
Not a fit: Patients who have not had a stroke or do not experience aphasia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for stroke patients with aphasia, enhancing their recovery and communication abilities.
How similar studies have performed: Previous research has shown promising results in using functional connectivity measures to predict treatment responses in stroke patients, indicating that this approach has potential for success.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Falconer, Isaac B — Boston University Medical Campus
- Study coordinator: Falconer, Isaac B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.