Investigating brain connectivity and its effects on development in children with congenital heart disease.
Does Altered Brain Connectivity Correlate with Developmental Outcomes and Executive Function in Congenital Heart Disease?
This study is looking at how changes in brain connections in kids with congenital heart disease might affect their development and thinking skills, so we can find better ways to support them as they grow up.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10889591 on NIH RePORTER |
What this research studies
This research explores how altered brain connectivity in children with congenital heart disease (CHD) relates to their developmental outcomes and executive function. By examining both in utero and postnatal factors, the study aims to identify better predictors of executive function impairment, which is crucial for independent living and mental health. The research utilizes advanced imaging techniques to analyze brain structure and connectivity, focusing on how various factors, including surgery and parenting, may influence neurodevelopment. The goal is to improve the allocation of services and interventions for affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research include children diagnosed with congenital heart disease, particularly those exhibiting signs of neurodevelopmental disabilities.
Not a fit: Patients without congenital heart disease or those who do not exhibit neurodevelopmental challenges may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved identification and intervention strategies for children with congenital heart disease, enhancing their cognitive and developmental outcomes.
How similar studies have performed: Previous research has shown promising results in understanding brain connectivity and its impact on cognitive function in similar populations, indicating that this approach has potential for success.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Chung, Ai Wern — Boston Children's Hospital
- Study coordinator: Chung, Ai Wern
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.