Investigating brain circuits involved in addiction
Genetic Targeting Core
['FUNDING_P30'] · UNIVERSITY OF ARIZONA · NIH-11111374
This study is looking at how substance use disorders change the way our brains work, especially in areas that control feelings of reward and stress, to help find new treatments that could benefit people struggling with addiction.
Quick facts
| Phase | ['FUNDING_P30'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ARIZONA (nih funded) |
| Locations | 1 site (TUCSON, UNITED STATES) |
| Trial ID | NIH-11111374 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how substance use disorders (SUD) affect brain circuitry, particularly in areas responsible for reward, stress response, and executive function. By examining the neural changes in regions like the basal ganglia and amygdala, the project aims to identify the neurotransmitters involved in addiction. The Genetic Targeting Core will provide tools and services to manipulate these brain circuits in a precise manner, helping to gather preliminary data that could lead to new treatment strategies for SUD. Patients may benefit from insights gained through this research that could inform future therapies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit are individuals struggling with substance use disorders.
Not a fit: Patients who do not have substance use disorders or related behavioral issues may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for substance use disorders by restoring normal brain function.
How similar studies have performed: Other research has shown promise in manipulating brain circuits to treat addiction, indicating that this approach could be effective.
Where this research is happening
TUCSON, UNITED STATES
- UNIVERSITY OF ARIZONA — TUCSON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NAVRATILOVA, EDITA — UNIVERSITY OF ARIZONA
- Study coordinator: NAVRATILOVA, EDITA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: addictive disorder