Investigating brain circuits and behavior using protein interaction modulators
Probing brain circuit and behavior with protein:protein interaction modulators
['FUNDING_R01'] · UNIVERSITY OF TEXAS MED BR GALVESTON · NIH-10992684
This study is looking at how certain proteins in brain cells affect mental health conditions, and it's trying to create new tools to better understand these issues, which could help develop better treatments for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS MED BR GALVESTON (nih funded) |
| Locations | 1 site (GALVESTON, UNITED STATES) |
| Trial ID | NIH-10992684 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding complex brain disorders, particularly psychiatric diseases, by exploring how protein interactions within brain cells affect neuronal excitability. The team aims to develop novel molecular probes that can help identify the mechanisms behind circuit deficits associated with these disorders. By using advanced techniques like bioluminescence-based high-throughput screening, they will test how these probes can influence brain function and potentially lead to better therapeutic options. Patients may benefit from improved drug designs that target specific brain circuit dysfunctions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with psychiatric disorders that involve circuit dysfunction, such as addiction or mood disorders.
Not a fit: Patients with purely physical health conditions unrelated to psychiatric disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for psychiatric disorders by providing insights into brain circuit mechanisms.
How similar studies have performed: Other research has shown promise in using molecular probes to understand brain function, indicating that this approach could yield valuable insights.
Where this research is happening
GALVESTON, UNITED STATES
- UNIVERSITY OF TEXAS MED BR GALVESTON — GALVESTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LAEZZA, FERNANDA — UNIVERSITY OF TEXAS MED BR GALVESTON
- Study coordinator: LAEZZA, FERNANDA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: addictive disorder