Investigating brain changes related to cognitive status after mild traumatic brain injury
Diffusion MRI Model Parameter Estimation to Study Brain Microstructure as it Relates to Cognitive Status in Mild Traumatic Brain Injury
This study is looking at how mild traumatic brain injuries can change the brain's structure and affect thinking skills, and it involves patients getting MRI scans to help us understand these changes better over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10896341 on NIH RePORTER |
What this research studies
This research focuses on understanding how mild traumatic brain injury (MTBI) affects brain microstructure and cognitive function. Using advanced diffusion MRI techniques, the study aims to identify changes in brain tissue that occur after an injury and how these changes relate to cognitive outcomes. By analyzing parameters such as axon integrity and cortical volume, researchers hope to provide insights into the long-term effects of MTBI on cognitive health. Patients may undergo MRI scans to help researchers gather data on brain structure and function over time.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have recently experienced a mild traumatic brain injury and are experiencing cognitive symptoms.
Not a fit: Patients with severe traumatic brain injuries or those with pre-existing neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for individuals recovering from mild traumatic brain injury.
How similar studies have performed: Previous research has shown promise in using diffusion MRI techniques to study brain microstructure, indicating that this approach may yield valuable insights.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Lui, Yvonne W — New York University School of Medicine
- Study coordinator: Lui, Yvonne W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.