Investigating brain changes in Alzheimer's disease and related dementias
Neuropathology Core
This study is looking at brain tissue from people with Alzheimer's and similar conditions to help us learn more about these diseases and find better treatments in the future.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10916435 on NIH RePORTER |
What this research studies
This research focuses on the detailed examination of brain tissue from individuals who have been diagnosed with Alzheimer's disease and related dementias. The Neuropathology Core will perform standardized evaluations of postmortem brain samples to understand the underlying pathology of these conditions. By collecting and analyzing both fixed and frozen autopsy materials, the research aims to support future studies that could lead to better understanding and treatment of Alzheimer's disease. The team, led by experts in molecular pathology, will ensure that the specimens are processed and characterized according to established criteria.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias who are willing to participate in postmortem evaluations.
Not a fit: Patients who are not diagnosed with Alzheimer's disease or related dementias may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of Alzheimer's disease, potentially leading to improved diagnostic and therapeutic strategies for patients.
How similar studies have performed: Previous research has shown success in utilizing postmortem brain tissue analysis to advance our understanding of neurodegenerative diseases, making this approach both established and promising.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Cohen, Mark — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Cohen, Mark
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.