Investigating brain changes and temperature in adults with obstructive sleep apnea
Official title: Brain Metabolites and Temperature Changes in Obstructive Sleep Apnea Adults
Funded at University of California Los Angeles · NIH-10939635 · Data updated 2026-11-12
This study is looking at how obstructive sleep apnea affects the brain in adults, especially how it might impact thinking and mood, and it’s for anyone who wants to understand more about their condition and help find better treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 6, 2024 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $711,226 |
| NIH project number | 1R01HL174651-01 |
| Project ID | NIH-10939635 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults diagnosed with obstructive sleep apnea.
✕Less likely to help
Patients without a diagnosis of obstructive sleep apnea or those under 21 years old may not benefit from this research.
What this research studies
This research focuses on understanding how obstructive sleep apnea (OSA) affects brain function and health in adults. It examines the relationship between intermittent hypoxia, brain metabolites, and temperature changes, which may contribute to cognitive and mood impairments. By using advanced imaging techniques, the study aims to identify the underlying mechanisms of brain injury associated with OSA, potentially leading to better treatment strategies. Participants may undergo non-invasive assessments to measure brain temperature and metabolite levels.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for adults suffering from obstructive sleep apnea.
How similar studies have gone: While the specific approach of this research is novel, related studies have shown that understanding brain metabolism and temperature can provide insights into neurological conditions.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Kumar, Rajesh — University of California Los Angeles
- Study coordinator: Kumar, Rajesh
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.