Investigating brain changes and temperature in adults with obstructive sleep apnea

Brain Metabolites and Temperature Changes in Obstructive Sleep Apnea Adults

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10939635

This study is looking at how obstructive sleep apnea affects the brain in adults, especially how it might impact thinking and mood, and it’s for anyone who wants to understand more about their condition and help find better treatments.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded)
Locations1 site (LOS ANGELES, UNITED STATES)
Trial IDNIH-10939635 on ClinicalTrials.gov

What this research studies

This research focuses on understanding how obstructive sleep apnea (OSA) affects brain function and health in adults. It examines the relationship between intermittent hypoxia, brain metabolites, and temperature changes, which may contribute to cognitive and mood impairments. By using advanced imaging techniques, the study aims to identify the underlying mechanisms of brain injury associated with OSA, potentially leading to better treatment strategies. Participants may undergo non-invasive assessments to measure brain temperature and metabolite levels.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults diagnosed with obstructive sleep apnea.

Not a fit: Patients without a diagnosis of obstructive sleep apnea or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for adults suffering from obstructive sleep apnea.

How similar studies have performed: While the specific approach of this research is novel, related studies have shown that understanding brain metabolism and temperature can provide insights into neurological conditions.

Where this research is happening

LOS ANGELES, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired brain injury

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.