Investigating brain aging in people with HIV and methamphetamine use
Official title: Brain Age of People with HIV and History of Methamphetamine Use
Funded at University of California, San Diego · NIH-11086035 · Data updated 2026-11-12
This study is looking at how HIV and methamphetamine use might speed up brain aging, and it's for people living with these conditions who want to understand how they affect brain health and thinking skills.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | May 15, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $180,235 |
| NIH project number | 5K01DA060092-02 |
| Project ID | NIH-11086035 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults living with HIV who have a history of methamphetamine use.
✕Less likely to help
Patients without HIV or those who have not used methamphetamine may not benefit from this research.
What this research studies
This research examines how HIV and methamphetamine use may accelerate brain aging. By utilizing advanced neuroimaging techniques, the study aims to estimate the 'brain age' of individuals, which reflects biological aging compared to chronological age. The research will analyze data from the Human Connectome Project and a local dataset to understand the combined effects of HIV and methamphetamine on brain health. Participants will undergo imaging assessments to help develop a model that predicts cognitive impairments associated with accelerated brain aging.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and interventions for cognitive decline in individuals with HIV and a history of methamphetamine use.
How similar studies have gone: Previous research has shown promising results in using neuroimaging to assess brain aging, indicating that this approach may yield valuable insights.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Lobo, Judith Diane — University of California, San Diego
- Study coordinator: Lobo, Judith Diane
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.