Investigating brain aging and cognitive decline in older African Americans
MRI markers of brain aging and risk factors for cognitive decline in older African Americans
This study is looking at how cultural and social factors affect brain health and memory in older African Americans, using brain scans to see how these factors might relate to the risk of Alzheimer's disease, and it’s designed for older adults who want to help us understand these important connections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rush University Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10408780 on NIH RePORTER |
What this research studies
This research focuses on understanding how culturally relevant psychosocial factors contribute to cognitive decline and the risk of Alzheimer's disease in older African Americans. Using MRI technology, the study will examine changes in brain structure and function over time, linking these changes to cognitive performance. By exploring these connections, the research aims to uncover the neurobiological mechanisms that underlie the higher rates of cognitive impairment in this population. Participants will undergo repeated assessments to track their cognitive health and brain integrity.
Who could benefit from this research
Good fit: Ideal candidates for this research are older African Americans who may be experiencing cognitive decline or are at risk for Alzheimer's disease.
Not a fit: Patients who are not of African American descent or those who do not have concerns about cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and targeted interventions for cognitive decline in older African Americans.
How similar studies have performed: While there has been significant research on cognitive decline in general, this study's focus on culturally relevant psychosocial factors in African Americans is relatively novel and underexplored.
Where this research is happening
Chicago, United States
- Rush University Medical Center — Chicago, United States (Active)
Researchers
- Principal investigator: Barnes, Lisa L — Rush University Medical Center
- Study coordinator: Barnes, Lisa L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.