Investigating brain activity patterns in Parkinson's disease motor symptoms
Oscillatory Neural Correlates of Motor Phenotypes in Parkinson Disease
['FUNDING_R01'] · MAYO CLINIC ROCHESTER · NIH-10992887
This study is looking at how the brain works in people with Parkinson's disease to find patterns that relate to symptoms like shaking and stiffness, so doctors can better customize deep brain stimulation treatments to help each person feel better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAYO CLINIC ROCHESTER (nih funded) |
| Locations | 1 site (ROCHESTER, UNITED STATES) |
| Trial ID | NIH-10992887 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the brain's electrical activity in patients with Parkinson's disease (PD) to identify specific patterns associated with different motor symptoms, such as tremors and rigidity. By recording local field potentials and single unit activity from key brain areas involved in movement, the study aims to uncover neurobiomarkers that can help tailor deep brain stimulation (DBS) treatments to individual patients. The goal is to improve decision-making for DBS therapy by linking these brain activity patterns to the severity and type of motor symptoms experienced by patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who experience varying motor symptoms.
Not a fit: Patients with Parkinson's disease who do not exhibit significant motor symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment options for patients with Parkinson's disease.
How similar studies have performed: Previous research has shown promise in using brain activity patterns to inform treatment strategies in neurological disorders, suggesting potential for success in this approach.
Where this research is happening
ROCHESTER, UNITED STATES
- MAYO CLINIC ROCHESTER — ROCHESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: INCE, NURI FIRAT — MAYO CLINIC ROCHESTER
- Study coordinator: INCE, NURI FIRAT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.